Autoinflammation of Unknown Cause

Links checked 23/03/18.

There are several autoinflammatory conditions that are already known about, including Sweet’s syndrome. However, there are some people that demonstrate the signs and symptoms associated with autoinflammatory conditions, but these signs and symptoms do not quite fit in with any known or specific autoinflammatory condition. This is called autoinflammation of unknown cause.

What are the symptoms of autoinflammation of unknown cause?

Common symptoms of autoinflammation of unknown cause include:

  • Fever (Simon et al, 2015).
  • Skin rash.
  • Muscle pain.
  • Joint pain or inflammation of one or more joints with redness, swelling and warmth.
  • Abdominal pain.
  • Diarrhoea.
  • Nausea.
  • Chest pain (caused by inflammation of the pleura or pericardium).
  • Enlarged lymph nodes.
  • Enlarged liver of spleen.
  • Red eyes.
  • Aphthous ulcers in the mouth or on the genitals (Ibid).

See ‘References’ to learn more about autoinflammation of unknown cause.


Simon, A. et al (2015) Autoinflammation of Unknown Cause. AUTOINFLAMMATION.EU (online). Updated 8/01/15 and accessed 23/03/18.

2012-2018 Sweet’s Syndrome UK


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