June 2nd is Sweet’s Syndrome UK Day. Share 5 key facts about Sweet’s syndrome to help spread awareness.
1. Sweet’s syndrome is a rare condition. Rare conditions affect less than 5 people per 10,000. Sweet’s syndrome probably affects no more than 3 people per 10,000.
2. Sweet’s syndrome is often referred to as a skin condition, but it doesn’t just affect the skin. It causes lots of other symptoms too, and can sometimes make a person seriously ill. On rare occasions, it’s life-threatening.
3. Sweet’s syndrome is a form of neutrophilic dermatosis. These conditions occur as a result of lots of white blood cells called neutrophils infiltrating the tissues. They can sometimes be a sign of underlying illness, including cancer.
4. Sweet’s syndrome is an autoinflammatory and not an autoimmune condition. Autoinflammatory conditions are caused by errors in the innate immune system, our most primitive, ‘hard-wired’ immune system. Autoimmune conditions involve the adaptive immune system, the part of the immune system that produces (auto) antibodies in response to antigens.
5. Sweet’s syndrome is still a poorly understood condition, but causes include cytokine dysregulation, hypersensitivity reaction, and genetic susceptibility. In regards to the latter, some people with Sweet’s syndrome, mainly Japanese, are more likely to have the genetic marker HLA-B54. However, this doesn’t mean that Sweet’s syndrome is a genetic condition.
Read more @ Key info.
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