How many people have Sweet’s syndrome?

How many people have Sweet’s syndrome?

Based upon the medical literature available, Sweet’s syndrome affects no more than 3 people per 10,000 (Zamanian and Ameri, 2007).

There are no official statistics to tell us for certain how many people have Sweet’s syndrome, and figures obtained via medical case-studies can vary. According to some of these studies, Sweet’s syndrome could affect as few as 0.27 people per 10,000 in some countries (treating figures from 1990 in Scotland as representative of the UK), or up to 3 people per 10,000 in others (Iran) (Ginarte and Toribio, 2011: 120; Zamanian and Ameri, 2007).

As Sweet’s syndrome can sometimes be triggered by infection, mainly upper respiratory tract infection, it tends to be more common in countries where people are more likely to develop infections (Ginarte and Toribio, 2011: 120).

The genetic marker, HLA-B54, is more likely to be found in people with Sweet’s syndrome. The frequency of HLA-B54 is higher in Japanese (17.9%) compared with white (0.6%) or black (0%) populations, suggesting a genetic predisposition among the Japanese for this condition (Bellus and Stumpf, 2003).

Further information.

Autoinflammatory Alliance (2015) Sweet’s Syndrome (SS); aka Acute Febrile Neutrophilic Dermatosis, Disease Comparison Chart (online).

What is a rare disease?


Bellus, G. and Stumpf, A. (2003) Neutrophilic Dermatosis, Acute Febrile. OMIM (online).

Ginarte, M. and Toribio, J. (2011) Sweet Syndrome. In Dr. Fang-Ping (Ed.) Autoimmune Disorders – Current Concepts and Advances from Bedside to Mechanistic Insights. Croatia or China: Intech, pp. 119-132 (PDF). 

Zamanian, A. and Ameri, A. (2007) Acute febrile neutrophilic dermatosis (Sweet’s syndrome): a study of 15 cases in Iran. International Journal of Dermatology, Jun;46(6):571-4 (PubMed).

2012-2018 Sweet’s Syndrome UK


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